Essential Estrogens® - Hormone Test
ssential Estrogens™ is a targeted urinary hormone test designed to evaluate estrogen metabolism specifically. This hormone test offers clinical insight into parent estrogens, key estrogen metabolites, and relevant ratios and is useful for initial estrogen assessment as well as follow-up testing to monitor response to therapies and/or to check levels of previously abnormal results.
Essential Estrogens® with Genomics
Personalize Patient Treatment Protocols with Genomic Testing
We are excited to announce that the addition of select genomic markers to our Essential Estrogens profile. Assessment of these select genomic markers (also known as SNPs) in conjunction with urine hormone testing, supports broadened clinical insight into women's and men's health concerns.
Genomic testing using these SNPs may provide awareness into an array of conditions for which the peri/menopausal and andropausal patient seek support such as anxiety and other mood shifts, cardiovascular disease, cardiometabolic syndrome, bone health and hormone detoxification capacity.
Complete Hormones with Genomics
Complete Hormones kit requisitions will now include the option for ordering one or more of the following SNPs:
MTHFR – Methylenetetrahydrofolate Reductase
Low bone mineral density and/or fracture risk
Potential risk of all cancers
Low levels of B vitamins, especially folate
Risk for cardiovascular disease and stroke
COMT – Catechol-O-Methyltransferase
Mood Disorders
Chronic, high levels of stress
Increased risk for fracture
High or imbalanced estrogen levels, especially 4-hydroxyestrogn
VDR – Vitamin D Receptor
Autoimmune diseases
Metabolic syndrome
Cancer risk and progression
Osteopenia/osteoporosis
CY1B1 – Cytochrome P450 1B1
Increased risk for cancers in specific populations
Exposure-specific cancers
Estrogen imbalance can produce challenging symptoms during the transitional periods of perimenopause/ menopause and andropause (male menopause) including:
Weight gain
Anxiety
Fatigue
Low sex drive and performance issues
Hair loss
Sleep disturbances
Mood instability
Brain fog
Hot flashes
Why use the Essential Estrogens profile?
In conventional hormone testing, basic parent hormones (estrogens, progesterone, etc.) are usually measured in blood. However, urinary hormone testing, as offered in Essential Estrogens, provides several advantages:
Urinary hormone testing provides a more comprehensive look at hormone metabolism, measuring basic parent hormones, as well as compounds produced from parent hormones
Emerging research reinforces the potential relationship of disease risk with downstream estrogen metabolites, which are not routinely measured in blood testing and not available in salivary testing
Available as a convenient at-home collection of a first-morning or 24-hour specimen
The Essential Estrogen test is a subpanel of Complete Hormones, a more comprehensive evaluation of sex- and steroid-hormone biomarkers.
Genova also offers an additional Complete Hormones sub-panel with targeted clinical utility:
Estrogen Metabolism Assessment – a focused measurement of specific hydroxyestrogens, providing a rapid, convenient way of assessing the balance between two estrogen biomarkers (2/16 ratio)
Test Type: Urine Test